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Development and clinical evaluation of a quantitative fluorescent immunoassay for detecting canine CRP
- Source :
- International Journal of Veterinary Science and Medicine, Vol 11, Iss 1, Pp 87-93 (2023)
- Publication Year :
- 2023
- Publisher :
- Taylor & Francis Group, 2023.
-
Abstract
- ABSTRACTCanine C-reactive protein (cCRP) is one of the major positive acute phase proteins in dogs and is commonly measured to detect and monitor systemic inflammation as well as the efficacy of treatment. Traditional methods for testing cCPR, including enzyme-linked immunosorbent assay (ELISA), have some drawbacks, such as a long time for diagnosis and the requirement of well-equipped laboratories. Therefore, there is a need for a rapid and precise diagnostic test for cCRP at point-of-care. This study assessed the accuracy, precision, and validated clinical effectiveness of a diagnostic test based on fluorescent lateral flow immunoassay to detect cCRP. For the standard cCRP concentration ranging from 0 to 200 μg/mL, the cCRP diagnostic test showed strong linearity with R2 of 0.9977 (p
Details
- Language :
- English
- ISSN :
- 23144599
- Volume :
- 11
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- International Journal of Veterinary Science and Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.f793a184c7be427dbd43066cbd88b83b
- Document Type :
- article
- Full Text :
- https://doi.org/10.1080/23144599.2023.2247250