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Human milk oligosaccharides, milk microbiome and infant gut microbiome modulate neonatal rotavirus infection

Authors :
Sasirekha Ramani
Christopher J. Stewart
Daniel R. Laucirica
Nadim J. Ajami
Bianca Robertson
Chloe A. Autran
Dhairyasheel Shinge
Sandya Rani
Sasirekha Anandan
Liya Hu
Josephine C. Ferreon
Kurien A. Kuruvilla
Joseph F. Petrosino
B. V. Venkataram Prasad
Lars Bode
Gagandeep Kang
Mary K. Estes
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Neonatal rotavirus infections are associated with gastrointestinal symptoms in some settings, but the role of host factors in clinical presentation is unclear. Here, Ramani et al. show that human milk oligosaccharides and microbiome are associated with symptomatic infection with neonatal strain G10P[11].

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.f78defa712ee45d3809a0e52edeacecb
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-07476-4