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Long-term survival analysis of masitinib in amyotrophic lateral sclerosis

Authors :
Jesus S. Mora
Walter G. Bradley
Delia Chaverri
María Hernández-Barral
Javier Mascias
Josep Gamez
Gisella M. Gargiulo-Monachelli
Alain Moussy
Colin D. Mansfield
Olivier Hermine
Albert C. Ludolph
Source :
Therapeutic Advances in Neurological Disorders, Vol 14 (2021)
Publication Year :
2021
Publisher :
SAGE Publishing, 2021.

Abstract

Background: A randomized, placebo-controlled phase III study (AB10015) previously demonstrated that orally administered masitinib (4.5 mg/kg/day) slowed rate of functional decline, with acceptable safety, in amyotrophic lateral sclerosis (ALS) patients having an ALS Functional Rating Scale-revised (ALSFRS-R) progression rate from disease onset to baseline of

Details

Language :
English
ISSN :
17562864
Volume :
14
Database :
Directory of Open Access Journals
Journal :
Therapeutic Advances in Neurological Disorders
Publication Type :
Academic Journal
Accession number :
edsdoj.f78aa62ba2b0457d8e5fbdaa8ef19004
Document Type :
article
Full Text :
https://doi.org/10.1177/17562864211030365