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Depletion and activation of microglia impact metabolic connectivity of the mouse brain
- Source :
- Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-14 (2023)
- Publication Year :
- 2023
- Publisher :
- BMC, 2023.
-
Abstract
- Highlights Microglial activation influences metabolic connectivity. Microglial depletion results in distinct decreases of metabolic connectivity. Metabolic connectivity increases in progranulin deficient mice. Cellular FDG allocation in progranulin deficient mice is shifted to microglia.
Details
- Language :
- English
- ISSN :
- 17422094
- Volume :
- 20
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Journal of Neuroinflammation
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.f789df68cf5a424e8eef5f896ae436b3
- Document Type :
- article
- Full Text :
- https://doi.org/10.1186/s12974-023-02735-8