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Maggot therapy for chronic ulcer: A retrospective cohort and a meta-analysis
- Source :
- Asian Journal of Surgery, Vol 37, Iss 3, Pp 138-147 (2014)
- Publication Year :
- 2014
- Publisher :
- Elsevier, 2014.
-
Abstract
- Background/Objective: Maggot wound therapy (MWT) has been used in various wounds including diabetic foot ulcers, venous leg ulcers, pressure ulcers, and acute surgical wounds. However, the efficacy of MWT therapy has been controversial. We therefore conducted a cohort study and a meta-analysis to assess MWT effects. Methods: A retrospective cohort study was performed in diabetic foot ulcer (DFU) patients who were treated with MWT or conventional wound therapy (CWT) in Thailand. The Kaplan-Meier curve was applied to estimate the healing probability. A meta-analysis was performed to pool our study with four previous cohort studies identified from Medline and Scopus. Results: The estimated incidence of wound healing was 5.7/100 (95% CI: 4.49, 7.32) patients-week, and the median time to healing was 14 weeks. The hazard ratio (HR) of wound healing was 7.87 times significantly higher in the MWT than the CWT (p
- Subjects :
- chronic ulcer
chronic wound
maggot
maggot wound therapy
wound therapy
Surgery
RD1-811
Subjects
Details
- Language :
- English
- ISSN :
- 10159584
- Volume :
- 37
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Asian Journal of Surgery
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.f7867c8935f941c0bc77ae3fb75aef81
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.asjsur.2013.09.005