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Effects of clove (Caryophyllus aromaticus L.) on the labeling of blood constituents with technetium-99m and on the morphology of red blood cells

Authors :
Severo de Paoli
Tania Santos Giani
Giuseppe Antonio Presta
Marcia Oliveira Pereira
Adenilson de Souza da Fonseca
José Brandão-Neto
Aldo da Cunha Medeiros
Sebastião David Santos-Filho
Mário Bernardo-Filho
Source :
Brazilian Archives of Biology and Technology, Vol 50, Iss spe, Pp 175-182 (2007)
Publication Year :
2007
Publisher :
Instituto de Tecnologia do Paraná (Tecpar), 2007.

Abstract

Clove (Caryophyllus aromaticus L.) has been used for clinical procedures. Blood constituents labeled with technetium-99m (99mTc) are used in nuclear medicine. The aim of this work was to evaluate the effects of clove extract on the labeling blood constituents with 99mTc and on the morphology of red blood cells. Blood samples were incubated with clove, stannous chloride and 99mTc. Plasma, blood cells, insoluble fractions of plasma and blood cells were separated. The radioactivity was counted and percentage of radioactivity (%ATI) to each blood fraction was calculated. The shape and morphometric parameter (perimeter/area ratio) were evaluated. Clove extract altered significantly (pO cravo-da-índia (Caryophyllus aromaticus L.) tem sido usado em tratamentos clínicos. Constituintes sangüíneos marcados com tecnécio-99m (99mTc) são usados em medicina nuclear O objetivo foi avaliar os efeitos de um extrato de cravo-da-índia na marcação de constituintes sangüíneos com 99mTc e na morfologia das hemácias. Amostras de sangue foram incubadas com cravo-da-índia, cloreto estanoso e 99mTc. Plasma, células sangüíneas, frações insolúveis do plasma e das células sangüíneas foram separadas. A porcentagem de radioatividade incorporada (% ATI) nestas frações foi calculada. Forma e relação perímetro/área das hemácias foram avaliadas. O extrato de cravo-da-índia alterou significativamente (p

Details

Language :
English
ISSN :
15168913 and 16784324
Volume :
50
Issue :
spe
Database :
Directory of Open Access Journals
Journal :
Brazilian Archives of Biology and Technology
Publication Type :
Academic Journal
Accession number :
edsdoj.f715e90b7d1145b196052e46ea5533fc
Document Type :
article
Full Text :
https://doi.org/10.1590/S1516-89132007000600022