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Development of Photonic Multi-Sensing Systems Based on Molecular Gates Biorecognition and Plasmonic Sensors: The PHOTONGATE Project

Authors :
Oscar Nieves
David Ortiz de Zárate
Elena Aznar
Isabel Caballos
Eva Garrido
Ramón Martínez-Máñez
Fabian Dortu
Damien Bernier
Beatriz Mengual-Chuliá
F. Xavier López-Labrador
Jens J. Sloth
Katrin Loeschner
Lene Duedahl-Olesen
Natalia Prado
Martín Hervello
Armando Menéndez
Rainer Gransee
Thomas Klotzbuecher
M. Clara Gonçalves
Fahimeh Zare
Ana Fuentes López
Isabel Fernández Segovia
Jose M. Barat Baviera
Jaime Salcedo
Sara Recuero
Santiago Simón
Ana Fernández Blanco
Sergio Peransi
Maribel Gómez-Gómez
Amadeu Griol
Source :
Sensors, Vol 23, Iss 20, p 8548 (2023)
Publication Year :
2023
Publisher :
MDPI AG, 2023.

Abstract

This paper presents the concept of a novel adaptable sensing solution currently being developed under the EU Commission-founded PHOTONGATE project. This concept will allow for the quantification of multiple analytes of the same or different nature (chemicals, metals, bacteria, etc.) in a single test with levels of sensitivity and selectivity at/or over those offered by current solutions. PHOTONGATE relies on two core technologies: a biochemical technology (molecular gates), which will confer the specificity and, therefore, the capability to be adaptable to the analyte of interest, and which, combined with porous substrates, will increase the sensitivity, and a photonic technology based on localized surface plasmonic resonance (LSPR) structures that serve as transducers for light interaction. Both technologies are in the micron range, facilitating the integration of multiple sensors within a small area (mm2). The concept will be developed for its application in health diagnosis and food safety sectors. It is thought of as an easy-to-use modular concept, which will consist of the sensing module, mainly of a microfluidics cartridge that will house the photonic sensor, and a platform for fluidic handling, optical interrogation, and signal processing. The platform will include a new optical concept, which is fully European Union Made, avoiding optical fibers and expensive optical components.

Details

Language :
English
ISSN :
14248220
Volume :
23
Issue :
20
Database :
Directory of Open Access Journals
Journal :
Sensors
Publication Type :
Academic Journal
Accession number :
edsdoj.f6da7ccc7ab94c7c90f31a578ff07bc3
Document Type :
article
Full Text :
https://doi.org/10.3390/s23208548