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Glycemic Effectiveness of Metformin-Based Dual-Combination Therapies with Sulphonylurea, Pioglitazone, or DPP4-Inhibitor in Drug-Naïve Korean Type 2 Diabetic Patients
- Source :
- Diabetes & Metabolism Journal, Vol 37, Iss 6, Pp 465-474 (2013)
- Publication Year :
- 2013
- Publisher :
- Korean Diabetes Association, 2013.
-
Abstract
- BackgroundThis study compared the glycemic effectiveness of three metformin-based dual therapies according to baseline hemoglobin A1c (HbA1c) to evaluate the appropriateness of the guideline enforced by the National Health Insurance Corporation of Korea for initial medication of type 2 diabetes (T2D).MethodsThis prospective observational study was conducted across 24 weeks for drug-naïve Korean T2D patients with HbA1c greater than 7.5%. Subjects were first divided into three groups based on the agent combined with metformin (group 1, gliclazide-modified release or glimepiride; group 2, pioglitazone; group 3, sitagliptin). Subjects were also classified into three categories according to baseline HbA1c (category I, 7.5%≤HbA1c
Details
- Language :
- English
- ISSN :
- 22336079 and 22336087
- Volume :
- 37
- Issue :
- 6
- Database :
- Directory of Open Access Journals
- Journal :
- Diabetes & Metabolism Journal
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.f61994b071fd4c148c10714bb34bf3ae
- Document Type :
- article
- Full Text :
- https://doi.org/10.4093/dmj.2013.37.6.465