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(5S)-3-Chloro-4-(2,5-dihydro-1H-pyrrol-1-yl)-5-[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyloxy]furan-2(5H)-one

Authors :
Jing-Pei Huo
Fu-Ling Xue
Zhao-Yang Wang
Jian-Hua Fu
Source :
Acta Crystallographica Section E, Vol 67, Iss 1, Pp o73-o73 (2011)
Publication Year :
2011
Publisher :
International Union of Crystallography, 2011.

Abstract

The title compound, C18H26ClNO3, was obtained via a tandem asymmetric Michael addition–elimination reaction of 3,4-dichloro-5-(S)-(l-menthyloxy)furan-2(5H)-one and 2,5-dihydro-1H-pyrrole in the presence of potassium fluoride. In the molecule, the nearly planar dihydropyrrole ring [maximum atomic deviation = 0.019 (3) Å] is oriented at a dihedral angle of 10.73 (8)° to the the nearly planar furanone ring [maximum atomic deviation = 0.011 (2) Å]; the cyclohexane ring adopts a chair conformation. In the crystal, molecules are linked via weak intermolecular C—H...O hydrogen bonds, forming supramolecular chains running along the b axis.

Subjects

Subjects :
Crystallography
QD901-999

Details

Language :
English
ISSN :
16005368
Volume :
67
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Acta Crystallographica Section E
Publication Type :
Academic Journal
Accession number :
edsdoj.f5cad66f814a4fb8932efa853e4ddc
Document Type :
article
Full Text :
https://doi.org/10.1107/S1600536810051226