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Insulin Resistance, Dyslipidemia and Cardiovascular Changes in a Group of Obese Children
- Source :
- Arquivos Brasileiros de Cardiologia, Vol 104, Iss 4, Pp 266-273 (2015)
- Publication Year :
- 2015
- Publisher :
- Sociedade Brasileira de Cardiologia (SBC), 2015.
-
Abstract
- Introduction: Obesity-related comorbidities are present in young obese children, providing a platform for early adult cardiovascular disorders. Objectives: To compare and correlate markers of adiposity to metabolic disturbances, vascular and cardiac morphology in a European pediatric obese cohort. Methods: We carried out an observational and transversal analysis in a cohort consisting of 121 obese children of both sexes, between the ages of 6 and 17 years. The control group consisted of 40 children with normal body mass index within the same age range. Markers of adiposity, plasma lipids and lipoproteins, homeostasis model assessment-insulin resistance, common carotid artery intima-media thickness and left ventricular diameters were analyzed. Results: There were statistically significant differences between the control and obese groups for the variables analyzed, all higher in the obese group, except for age, high-density lipoprotein cholesterol and adiponectin, higher in the control group. In the obese group, body mass index was directly correlated to left ventricular mass (r=0.542; p=0.001), the homeostasis model assessment-insulin resistance (r=0.378; p=
Details
- Language :
- English, Portuguese
- ISSN :
- 16784170
- Volume :
- 104
- Issue :
- 4
- Database :
- Directory of Open Access Journals
- Journal :
- Arquivos Brasileiros de Cardiologia
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.f5b84bfe367744189339bf3931e2ba9d
- Document Type :
- article
- Full Text :
- https://doi.org/10.5935/abc.20140206