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The structure of Zika virus NS5 reveals a conserved domain conformation

Authors :
Boxiao Wang
Xiao-Feng Tan
Stephanie Thurmond
Zhi-Min Zhang
Asher Lin
Rong Hai
Jikui Song
Source :
Nature Communications, Vol 8, Iss 1, Pp 1-6 (2017)
Publication Year :
2017
Publisher :
Nature Portfolio, 2017.

Abstract

The recent outbreak of Zika virus is a major worldwide health concern and effective drugs are currently not available. Here the authors present the structure of Zika non-structural protein 5 and identify a potential drug-binding site, which might facilitate the development of novel antivirals.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723 and 47169486
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.f4e963abfda47169486b44a57c00ed7
Document Type :
article
Full Text :
https://doi.org/10.1038/ncomms14763