Human papilloma virus (HPV) infection is associated with HIV-1 infection and AIDS in HIV-infected adult patients from Zaria, Northern Nigeria

In order to provide preliminary information on the association between cumulative HPV-infection and HIV-1infection, we assayed serum IgG antibodies to HPV in 63 HIV-1 infected adults and 26 apparently healthy HIV-negative adults in Zaria, Northern Nigeria. One (3.8%) of the healthy adults and 26 (41.3%) of the HIV-patients were HPV IgG seropositive. On multivariate analyses, CD4-cell countless than 200cells/ul was the only independent predictor of HPV IgG seropositivity among HIV-infected patients. Our results suggest that in HIV-infected patients, HPV-infection is associated with significant immunosuppresion or AIDS.