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Network enhancement as a general method to denoise weighted biological networks

Authors :
Bo Wang
Armin Pourshafeie
Marinka Zitnik
Junjie Zhu
Carlos D. Bustamante
Serafim Batzoglou
Jure Leskovec
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Technical noise in experiments is unavoidable, but it introduces inaccuracies into the biological networks we infer from the data. Here, the authors introduce a diffusion-based method for denoising undirected, weighted networks, and show that it improves the performances of downstream analyses.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.f42c026bf24c03abbdc755b39fedc1
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-05469-x