Mononeuropathy multiplex as an uncommon presentation of intravascular lymphoma: A case report

Key Clinical Message Although intravascular lymphoma rarely presents with peripheral neuropathy, learning about this presentation can lead to timely diagnosis and improved prognosis in patients with intravascular lymphoma. Abstract A 64‐year‐old man presented with asymmetric paresthesia and subsequent weakness of his feet and a 10 kg weight loss over 40 days. Electrodiagnostic studies revealed distal axonal sensory‐motor polyneuropathy with ongoing axonal loss. A peroneal nerve biopsy showed intravascular proliferation of CD‐20 positive lymphocytes, which suggested intravascular large B‐cell lymphoma.