Effect of gender, age and season on serum 25-hydroxyvitamin D level

Authors :: WANG Dan-chen, YIN Yi-cong, YU Song-lin, ZHANG Rui-li, GAO Xue-hui, LI Hong-lei, CHENG Xin-qi, QIU Ling
Source :: Jichu yixue yu linchuang, Vol 40, Iss 2, Pp 151-154 (2020)
Publication Year :: 2020
Publisher :: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College., 2020.
Abstract: Objective To explore the effect of gender, age and season on serum 25-hydroxyvitamin D(25OHD). Methods Clinical data was collected from the laboratory information system at the Peking Union Medical College Hospital from December 2014 to October 2018. A total of 34 062 25OHD samples were obtained and analyzed. 25OHD concentrations were measured using a Roche e601 automatic analyzer. Regression analysis was used to explore the effect of gender, age and season on 25OHD level. Results The median serum 25OHD concentration was significantly higher in males than that in females(P＜0.001). The median serum 25OHD concentration at the peak level in August was 22.1 ng/mL. Regression analysis revealed that summer had the highest impact on 25OHD (standardization coefficient=0.273). Conclusions Gender and season significantly affected serum 25OHD levels.