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Accurate, scalable and integrative haplotype estimation

Authors :
Olivier Delaneau
Jean-François Zagury
Matthew R. Robinson
Jonathan L. Marchini
Emmanouil T. Dermitzakis
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Haplotype information inferred by phasing is useful in genetic and genomic analysis. Here, the authors develop SHAPEIT4, a phasing method that exhibits sub-linear running time, provides accurate haplotypes and enables integration of external phasing information.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.f38d241b124818a2dec135ef6a75e5
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-13225-y