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Clinical characteristics, treatment modalities and outcome of coronavirus disease 2019 patients treated at thisday dome isolation and treatment centre, federal capital territory Abuja, Nigeria

Authors :
Sylvanus Akhalufo Okogbenin
Cyril Oshomah Erameh
Ola Chikerendu Egbuta
Kelly Ohis Iraoyah
Joy Thelma Onyebujoh
Christian Ehigbor Erohubie
Akolo Yohanna Jaggu
Raymond Onovo
Mercy Avbuluimen
Modupeola Ajibike Odewale
Elizabeth Ebosebhanlen Enigbe
Ehinomen Cordilia Ifada
Esther Osemudiamen Okogbenin
Source :
Nigerian Postgraduate Medical Journal, Vol 28, Iss 2, Pp 81-87 (2021)
Publication Year :
2021
Publisher :
Wolters Kluwer Medknow Publications, 2021.

Abstract

Introduction: Coronavirus disease 2019 (COVID-19), a highly transmissible viral infection has spread worldwide causing exponential increase in morbidity and mortality. But so far, there is limited information available to describe the presenting characteristics, outcomes and treatment modalities of COVID-19 patients in Nigeria. This study aimed to describe the demographic and clinical characteristics, underlying comorbidities, treatment modalities and outcomes of patients isolated and treated in a repurposed COVID-19 isolation and treatment centre in Abuja, Nigeria. Materials and Methods: A retrospective study which reviewed the medical records of 300 confirmed COVID-19 patients isolated and treated according to the World Health Organisation and Nigeria Centre for Disease Control guidelines between 22nd July and 26th October, 2020 in ThisDay Dome Isolation and Treatment Centre. Data collected from the medical records include demographics, clinical features, treatment measures and outcomes. Results: Out of 300 patients studied, 61.0% were male. The mean age of the participants was 38.2 ± 14.7. Less than half of the patients (40.3%) had one or more underlying comorbidities with hypertension the most common co-morbidity. Majority (62%) of patients were mildly symptomatic, 33% were asymptomatic while only 2% were severely symptomatic. The most common presenting symptoms include cough 34.0%, fever 30.3%, anosmia 28.7% and dysgeusia 22.7%. Older age (P < 0.001), tertiary education and the presence of underlying comorbidity (P < 0.001) were significantly associated with symptomatic presentation of COVID-19. The median duration of time between positive laboratory testing and presentation for treatment was 5 days (0–29). All patients were treated with a combination of Ivermectin, Azithromycin, Zinc and Vitamin C with no recorded death. The median length of stay at facility was 9 days. Conclusion: Close attention should be given to patients with co-morbidities as an inefficient management of such co-morbidities could lead to mortalities which may not be directly attributable to COVID-19.

Details

Language :
English
ISSN :
11171936 and 24686875
Volume :
28
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Nigerian Postgraduate Medical Journal
Publication Type :
Academic Journal
Accession number :
edsdoj.f2c9b672f9644d5983fc796d1b0ed425
Document Type :
article
Full Text :
https://doi.org/10.4103/npmj.npmj_532_21