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Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells

Authors :
Hiroki Ikeda
Masamitsu Sone
Shinya Yamanaka
Takuya Yamamoto
Source :
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Publication Year :
2017
Publisher :
Nature Portfolio, 2017.

Abstract

Higher-order chromatin organization regulates the expression of transcriptional programs that control cell function. Here, the authors show that chromatin interaction profiles and nuclear positions at developmental gene loci differ between human somatic and pluripotent stem cells.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.f2abb74fe82443a5a79daa922416e7d6
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-017-01679-x