Back to Search Start Over

The Incidence and Characteristics of Thrombosis in Patients with Immune thrombocytopenia: A Retrospective Cohort Study

Authors :
Zhang P
Cai Y
Ge F
Zhu Z
Sun K
Source :
International Journal of General Medicine, Vol Volume 17, Pp 2021-2027 (2024)
Publication Year :
2024
Publisher :
Dove Medical Press, 2024.

Abstract

Ping Zhang, Yanan Cai, Fei Ge, Zunmin Zhu, Kai Sun Department of Hematology, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhengzhou, People’s Republic of ChinaCorrespondence: Kai Sun, Department of Hematology, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, #7 Weiwu Road, Zhengzhou, People’s Republic of China, Email sunkai900@163.comIntroduction: This study aims to investigate the incidence, clinical characteristics, and prognosis of thrombosis in Chinese patients with immune thrombocytopenia (ITP).Methods: This was a single-center, retrospective study of adult patients with ITP at the Henan Provincial People’s Hospital from January 2018 to June 2023.Results: A total of 3216 adult patients with primary ITP were included in the study period, with 25 (0.93%) having thrombotic events. The average age of 25 patients with thrombosis is 62.76± 12.79 years, including 11 males and 14 females. In addition, among the 25 thrombotic events, 19 cases were arterial thrombosis (AT), and 6 cases were venous thrombosis (VT). The incidence of AT is higher than that of VT (P=0.009). There was no obvious difference in clinical characteristics between the two groups. The median platelet count at the time of thrombosis in 25 patients was 35 (23, 52) × 109/L. At the onset of thrombosis, 23 patients (92.0%) had a low PLT (< 100× 109/L). One patient with ischemic stroke died in the hospital due to severe infection.Conclusion: ITP may be considered a bleeding disorder with a high risk of thrombosis, and AT is more common than VT in the Chinese population.Keywords: immune thrombocytopenia, arterial thrombosis, venous thrombosis, platelet, hemorrhagic disease

Details

Language :
English
ISSN :
11787074
Volume :
ume 17
Database :
Directory of Open Access Journals
Journal :
International Journal of General Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.f2423f09703b421a8800ee060b55deb5
Document Type :
article