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Multicentre interlaboratory analysis of routine susceptibility testing with a challenge panel of resistant strains
- Source :
- Journal of Global Antimicrobial Resistance, Vol 28, Iss , Pp 125-129 (2022)
- Publication Year :
- 2022
- Publisher :
- Elsevier, 2022.
-
Abstract
- ABSTRACT: Objectives: In order to elaborate a new national challenge panel of resistant Gram-negative bacilli and Gram-positive cocci strains for the validation of routine antimicrobial susceptibility testing (AST) methods, an interlaboratory evaluation was organised. Methods: The results of 12 well-characterised multidrug-resistant strains tested by nine laboratories using local disk diffusion (DD) and automated AST (AUST) methods were compared with the reference broth microdilution method. Results: Overall categorical agreement ranged from 70% to 100% both for DD and AUST and was >90% for all but one strain for all antibiotics. Conclusion: Our multicentre AST study showed good reproducibility and the panel can be used as national resistant reference strains for routine AST validation.
Details
- Language :
- English
- ISSN :
- 22137165
- Volume :
- 28
- Issue :
- 125-129
- Database :
- Directory of Open Access Journals
- Journal :
- Journal of Global Antimicrobial Resistance
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.f200bed75abd4cfa9291c376e01f1f7c
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.jgar.2021.12.020