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Microbiota-derived acetate enhances host antiviral response via NLRP3
- Source :
- Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
- Publication Year :
- 2023
- Publisher :
- Nature Portfolio, 2023.
-
Abstract
- The NLRP3 inflammasome plays a pivotal role in clearing viral respiratory infection, but the molecular mechanism is not fully known. Here authors show that acetate, produced by gut bacteria, may enhance NLRP3-mediated type I interferon production following influenza infection in mice.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 14
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.f1ef849a44449b71611edcfea5787
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-023-36323-4