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Role of targeted therapy in the treatment of HER-2-positive breast cancer brain metastases
- Source :
- Опухоли женской репродуктивной системы, Vol 12, Iss 1, Pp 46-51 (2016)
- Publication Year :
- 2016
- Publisher :
- ABV-press, 2016.
-
Abstract
- Brain metastases are detectable in 25–35 % of patients with progressive HER-2-positve breast cancer. Even after spreading metastases into the brain, chemotherapy in combination with anti-HER- 2 therapy improves survival due to better control of the systemic disease. The paper presents the results of investigations substantiating the use of anti-HER-2 targeting agents, as well as the innovative agent T-DM1 to treat brain metastases.
Details
- Language :
- Russian
- ISSN :
- 19944098 and 19998627
- Volume :
- 12
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Опухоли женской репродуктивной системы
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.f195e60b5004d29b0a2524764f3d9a8
- Document Type :
- article
- Full Text :
- https://doi.org/10.17650/1994-4098-2016-12-1-46-51