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Toward a rational design of combination therapy in cancer
- Source :
- OncoImmunology, Vol 4, Iss 11 (2015)
- Publication Year :
- 2015
- Publisher :
- Taylor & Francis Group, 2015.
-
Abstract
- By merging computational systems modeling and experimental approaches, we have uncovered treatments reprogramming pro-angiogenic monocytes present in breast tumor into immunologically potent cells capable of mediating an anti-tumor immune response. The unraveled pathways and ligands which underlie monocyte pro-angiogenic activity have a strong predictive value for breast cancer patient relapse – free survival.
Details
- Language :
- English
- ISSN :
- 2162402X
- Volume :
- 4
- Issue :
- 11
- Database :
- Directory of Open Access Journals
- Journal :
- OncoImmunology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.f18f4cd53f8b41c3a35b804b97aee72d
- Document Type :
- article
- Full Text :
- https://doi.org/10.1080/2162402X.2015.1046674