Back to Search
Start Over
A high rate of CLL phenotype lymphocytes in autoimmune hemolytic anemia and immune thrombocytopenic purpura
- Source :
- Haematologica, Vol 93, Iss 1 (2008)
- Publication Year :
- 2008
- Publisher :
- Ferrata Storti Foundation, 2008.
-
Abstract
- Minor CLL-like clones are found in ~3% of healthy individuals. AIHA and ITP are common in CLL and may be causally linked. We investigated the presence of CLL phenotype lymphocytes in 11 cases of primary AIHA, 18 of ITP and 2 of Evans’ Syndrome, compared with 26 age-matched healthy controls. A population of ‘CLL phenotype’ was seen in 6/31 patients compared to 1/26 healthy controls (χ2=3.9; p=0.05). Such clones may be important in the pathogenesis of autoimmune blood disorders.
- Subjects :
- Diseases of the blood and blood-forming organs
RC633-647.5
Subjects
Details
- Language :
- English
- ISSN :
- 03906078 and 15928721
- Volume :
- 93
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Haematologica
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.f14c6852c30640e1892a50fa99d057d2
- Document Type :
- article
- Full Text :
- https://doi.org/10.3324/haematol.11822