Effect of phacoemulsification on ocular surface and corneal endothelial cells in cataract patients with diabetes mellitus

AIM:To study the effects of phacoemulsification on ocular surface and corneal endothelial cells in cataract patients with diabetes mellitus.METHODS: This study used a retrospective analysis of the clinical data to compare curative effect, the research object was 98 cases(98 eyes)of cataract patients with phacoemulsification from January 2016 to December 2016 in our hospital. Patients were divided into the observation group and the control group according to whether diabetes merged. The observation group had 50 cases of cataract patients with diabetes, the control group had 48 cases of pure cataract patients. Two groups of patients underwent phacoemulsification surgery and transparent corneal incision, surgeries were completed by the same doctor, no xeroma before surgery. Preoperative glycemic control was normal for diabetic patients, no changes in eye fundus. Observation of ocular surface at postoperative 1, 3, 7d and 1mo was taken. Dry eye symptoms, lacrimal film breakup time(BUT), corneal fluorescein staining(FL)score, SchirmerⅠtest(SⅠt)and corneal endothelial cell density were compared. RESULTS: Dry eye symptom score of the two groups before and after operation had significant difference; data of the observation group at postoperative 7d and 1mo was significantly higher than that of the control group, there was statistical significance(PP>0.05). BUT of the two groups before and after surgery showed significant difference; data of the observation group at 7d and 1mo after operation was significantly lower than that of the control group, there was statistical significance(PP>0.05). The FL score of the two groups before and after surgery had significant difference, and at 3,7d and 1mo after operation, data of the observation group was significantly higher than that of the control group, there was statistical significance(PP>0.05). The two groups' before and after surgery SⅠt had significant difference, at 1, 3, 7d and 1mo after operation, data of the observation group was significantly higher than that of the control group, there was statistical significance(PPCONCLUSION: Phacoemulsification has significant effects on tear film break-up time, SⅠt and dry eye symptoms in patients with diabetes mellitus, which may be related to the impaired repair ability of diabetic patients.