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Decreased serum C1Q/TNF-related protein 4 concentrations are associated with type 2 diabetes mellitus
- Source :
- Therapeutic Advances in Endocrinology and Metabolism, Vol 12 (2021)
- Publication Year :
- 2021
- Publisher :
- SAGE Publishing, 2021.
-
Abstract
- Objective: To detect serum C1Q/TNF-related protein 4 (CTRP4) concentrations in patients with newly diagnosed type 2 diabetes mellitus (T2DM) and evaluate the correlation between CTRP4 and other variables in T2DM. Method: Sixty-five patients with newly diagnosed T2DM and eighty-nine healthy volunteers were enrolled in this study. Anthropometric and biochemical data of the study participants was collected, and serum CTRP4 concentrations were detected by enzyme-linked immunosorbent assay (ELISA) kit. The correlation between serum CTRP4 and other indexes was analyzed by Spearman correlation analysis. Trend χ 2 test and binary multivariate stepwise logistic regression were performed to assess the correlation between CTRP4 and the risk of T2DM. Results: Serum CTRP4 concentrations in the T2DM group were significantly lower than those in the control group ( P
- Subjects :
- Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Subjects
Details
- Language :
- English
- ISSN :
- 20420196 and 20420188
- Volume :
- 12
- Database :
- Directory of Open Access Journals
- Journal :
- Therapeutic Advances in Endocrinology and Metabolism
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.f0a432b53d664ad3b1f6265304777661
- Document Type :
- article
- Full Text :
- https://doi.org/10.1177/20420188211059884