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Deep learning-integrated MRI brain tumor analysis: feature extraction, segmentation, and Survival Prediction using Replicator and volumetric networks

Authors :
Deependra Rastogi
Prashant Johri
Massimo Donelli
Seifedine Kadry
Arfat Ahmad Khan
Giuseppe Espa
Paola Feraco
Jungeun Kim
Source :
Scientific Reports, Vol 15, Iss 1, Pp 1-27 (2025)
Publication Year :
2025
Publisher :
Nature Portfolio, 2025.

Abstract

Abstract The most prevalent form of malignant tumors that originate in the brain are known as gliomas. In order to diagnose, treat, and identify risk factors, it is crucial to have precise and resilient segmentation of the tumors, along with an estimation of the patients’ overall survival rate. Therefore, we have introduced a deep learning approach that employs a combination of MRI scans to accurately segment brain tumors and predict survival in patients with gliomas. To ensure strong and reliable tumor segmentation, we employ 2D volumetric convolution neural network architectures that utilize a majority rule. This method helps to significantly decrease model bias and improve performance. Additionally, in order to predict survival rates, we extract radiomic features from the tumor regions that have been segmented, and then use a Deep Learning Inspired 3D replicator neural network to identify the most effective features. The model presented in this study was successful in segmenting brain tumors and predicting the outcome of enhancing tumor and real enhancing tumor. The model was evaluated using the BRATS2020 benchmarks dataset, and the obtained results are quite satisfactory and promising.

Details

Language :
English
ISSN :
20452322
Volume :
15
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Scientific Reports
Publication Type :
Academic Journal
Accession number :
edsdoj.bf507e0ef7f4b7ca3a5728d2d8483b0
Document Type :
article
Full Text :
https://doi.org/10.1038/s41598-024-84386-0