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Elimination of Cas9-dependent off-targeting of adenine base editor by using TALE to separately guide deaminase to target sites

Authors :
Yang Liu
Jizeng Zhou
Ting Lan
Xiaoqing Zhou
Yang Yang
Chuan Li
Quanjun Zhang
Min Chen
Shu Wei
Shuwen Zheng
Lingyin Cheng
Yuling Zheng
Liangxue Lai
Qingjian Zou
Source :
Cell Discovery, Vol 8, Iss 1, Pp 1-5 (2022)
Publication Year :
2022
Publisher :
Nature Publishing Group, 2022.

Subjects

Subjects :
Cytology
QH573-671

Details

Language :
English
ISSN :
20565968
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Cell Discovery
Publication Type :
Academic Journal
Accession number :
edsdoj.bf38975bde824343995145f160c77e83
Document Type :
article
Full Text :
https://doi.org/10.1038/s41421-022-00384-4