EPIDEMIOLOGICAL PATTERNS OF CHRONIC HBV-INFECTION IN FAMILY CASES

Analysis and examination of 220 families allowed to reveal the presence of interfamily concentration of chronic HBV-infection in 30.9% cases. The role of interdependence of the different haptoglobin (HP) phenotypes with the genotypic properties of the virus in the formation of «family cases» of chronic hepatitis В (CHB) were defined and the peculiarities of the profile of HBV markers depending on the carrier and HP viral genotype in children from family cases with CHB were discovered.