Eliciting the impacts of cellular noise on metabolic trade-offs by quantitative mass imaging

Authors :: A. E. Vasdekis
H. Alanazi
A. M. Silverman
C. J. Williams
A. J. Canul
J. B. Cliff
A. C. Dohnalkova
G. Stephanopoulos
Source :: Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Publication Year :: 2019
Publisher :: Nature Portfolio, 2019.
Abstract: How cellular noise impacts metabolic trade-offs remains unknown. Here, the authors use a quantitative single-cell mass imaging strategy to reveal that cellular noise impacts cellular biomass and triacylglycerol accumulation, as well as protein and fatty-acid recycling under starvation, differently.

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