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Turning up the heat on essential E. coli genes
- Source :
- Molecular Systems Biology, Vol 19, Iss 10, Pp n/a-n/a (2023)
- Publication Year :
- 2023
- Publisher :
- Springer Nature, 2023.
-
Abstract
- Temperature‐sensitive (TS) alleles create tunable thermoswitches to deplete essential cellular activities and are used to dissect gene function. In their recent study, Link and colleagues (Schramm et al 2023) use a CRISPR‐based approach to systematically create TS alleles across essential genes in E. coli.
- Subjects :
- Biology (General)
QH301-705.5
Medicine (General)
R5-920
Subjects
Details
- Language :
- English
- ISSN :
- 17444292
- Volume :
- 19
- Issue :
- 10
- Database :
- Directory of Open Access Journals
- Journal :
- Molecular Systems Biology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.bebc10ce873408fb7c6be78ea13fce7
- Document Type :
- article
- Full Text :
- https://doi.org/10.15252/msb.202311933