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Racial and ethnic differences in circulating N-terminal pro-brain-type natriuretic peptide (NT-proBNP) in US adults
- Source :
- American Journal of Preventive Cardiology, Vol 15, Iss , Pp 100526- (2023)
- Publication Year :
- 2023
- Publisher :
- Elsevier, 2023.
-
Abstract
- Background: The presence and interpretation of racial and ethnic differences in circulating N-terminal pro-brain-type natriuretic peptide (NT-proBNP), a diagnostic biomarker for heart failure, are controversial. Objective: To examine racial and ethnic differences in NT-proBNP levels among the general US adult population. Methods: We performed a cross-sectional analysis of data from the 1999–2004 National Health and Nutrition Examination Survey (NHANES). We included 4717 non-Hispanic White, 1675 non-Hispanic Black, and 2148 Mexican American adults aged 20 years or older without a history of cardiovascular disease. We examined the associations of race and ethnicity with NT-proBNP using linear and logistic regression models in the overall population and in a younger, ‘healthy’ subsample. Results: The mean age was 45 years. Median NT-proBNP levels were significantly lower among Black (29.3 pg/mL) and Mexican American adults (28.3.4 pg/mL) compared to White adults (49.1pg/mL, P-values
Details
- Language :
- English
- ISSN :
- 26666677
- Volume :
- 15
- Issue :
- 100526-
- Database :
- Directory of Open Access Journals
- Journal :
- American Journal of Preventive Cardiology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.bdf7710648c0497cbcbdb5a93d93cd29
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.ajpc.2023.100526