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Epigenetics and diabetes mellitus
- Source :
- The Egyptian Journal of Internal Medicine, Vol 28, Iss 2, Pp 39-51 (2016)
- Publication Year :
- 2016
- Publisher :
- SpringerOpen, 2016.
-
Abstract
- Epigenetic mechanisms were shown to be involved in the control of endocrine cell fate decision, islet differentiation, β-cell identity, proliferation, and mature function. The pathologic mechanisms involved in the development of type 1 diabetes may include DNA methylation, histone modification, microRNA, and molecular mimicry. These mechanisms may act through the regulation of gene expression.
- Subjects :
- diabetes
epigenetic
gene expression
Internal medicine
RC31-1245
Subjects
Details
- Language :
- English
- ISSN :
- 11107782 and 20909098
- Volume :
- 28
- Issue :
- 2
- Database :
- Directory of Open Access Journals
- Journal :
- The Egyptian Journal of Internal Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.bd54cc242b664f25b48638f809eb0000
- Document Type :
- article
- Full Text :
- https://doi.org/10.4103/1110-7782.193890