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Transcriptional activity and strain-specific history of mouse pseudogenes

Authors :
Cristina Sisu
Paul Muir
Adam Frankish
Ian Fiddes
Mark Diekhans
David Thybert
Duncan T. Odom
Paul Flicek
Thomas M. Keane
Tim Hubbard
Jennifer Harrow
Mark Gerstein
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Pseudogenes are key markers of genome remodelling processes. Here the authors present genome-wide annotation of the pseudogenes in the mouse reference genome and 18 inbred mouse strains, update human pseudogene annotations, and characterise the transcription and evolution of mouse pseudogenes.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.bc3bf2d1f24949899d576df8a558a91e
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-17157-w