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Effect of β-hydroxybutyrate acid on gene expression levels of antioxidant biomarkers and growth hormone–related genes in liver cell culture

Authors :
Mohsin Muhammad Ali
Zhou Xiaojing
Huiru Yu
Shen Wenxiang
He Baoxiang
Sobiech Przemysław
Pierzchała Mariusz
Ogłuszka Magdalena
Starzyński Rafał
Kalra Garima
Deshmukh Bharti
Thangarasu Revathy
Kashyap Neeraj
Czarnik Urszula
Lepczyński Adam
Woźniakowski Grzegorz
Pareek Chandra S.
Source :
Journal of Veterinary Research, Vol 68, Iss 2, Pp 313-324 (2024)
Publication Year :
2024
Publisher :
Sciendo, 2024.

Abstract

In dairy cattle, oxidative stress is a predominant problem associated with diseases and reproductive health issues. This study aimed to detect the variation in the antioxidant biomarkers by adding different concentrations of β-hydroxybutyric acid (BHBA) and sought to elucidate its effects on the gene expression levels of growth hormone (GH) and antioxidant biomarkers in bovine hepatocytes.

Details

Language :
English
ISSN :
24508608
Volume :
68
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Journal of Veterinary Research
Publication Type :
Academic Journal
Accession number :
edsdoj.bb19090e6994683a952c50d8751a404
Document Type :
article
Full Text :
https://doi.org/10.2478/jvetres-2024-0037