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The Effect of Quercus coccifera L. Extract on the Necrosis of Random-pattern Skin Flaps in Rats
- Source :
- Haseki Tıp Bülteni, Vol 57, Iss 3, Pp 249-254 (2019)
- Publication Year :
- 2019
- Publisher :
- Galenos Yayinevi, 2019.
-
Abstract
- Aim:Ischemia-reperfusion injury is an important cause of flap loss. We investigated effects of Quercus coccifera L. extract known to have anti-oxidant and anti-inflammatory activity on skin flap viability.Methods:Eighteen Wistar rats were used. Random-pattern skin flaps, 9x3 cm in size, were applied on rats back and then the rats were divided into three groups. Following surgery, 2 cc of nitrofurazone cream and 2 cc of Q. coccifera L. water extract were applied daily in groups 2 and 3, respectively. Group 1 received no treatment after surgery. The percentage of necrosis on the flaps was calculated and histopathological examination of the tissue samples was made on day 7.Results:The mean percentage of necrosis was 44.7%, 42.5% and 21.8% group 1, 2 and 3, respectively. The percentage of necrosis was statistically significantly lower in group 3 than in groups 1 and 2 (p
- Subjects :
- Quercus coccifera L.
necrosis
skin flap
Medicine
Medicine (General)
R5-920
Subjects
Details
- Language :
- English, Turkish
- ISSN :
- 13020072 and 21472688
- Volume :
- 57
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Haseki Tıp Bülteni
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.bb0a831298974b6684fd9789313ceee6
- Document Type :
- article
- Full Text :
- https://doi.org/10.4274/haseki.galenos.2018.4533