Trendanalysen zur Inzidenz und Mortalität an Krebs in Deutschland seit 1970

The present paper continues a work that has recently begun to estimate long-term incidence rates for Germany starting from 1970 up until 2010 (Haberland et al. 2014). National incidence is estimated by multiplying modeled national mortality with modeled incidence to mortality ratios obtained from regional German cancer registries. To achieve a greater stability in the results the included indicators are previously estimated (smoothed) using joinpoint models. Regarding the analyzed cancer sites, breast cancer incidence rates in women and prostate cancer incidence rates in men showed highest increase since 1970. These developments are accompanied by a decline in the corresponding mortality rates since the 1990s. The estimated incidence rates of colorectal cancer in both sexes increased since 1970 for more than 20 years with a higher level in men. However, since the 1990s the rates have stagnated and even declined in the last decade. Again, the standardized mortality rates are declining since the mid-1990s. The estimated lung cancer incidence and mortality rates run mainly parallel in both sexes. However, in men the standardized rates only increase in the 1970s and have declined significantly since the 1990s. In contrast, in women the incidence and mortality rates rise permanently for the whole observation period, at a lower level compared to men.