Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons

α-Synuclein aggregation contributes to Parkinson’s disease and related disorders. Here the authors investigate patterns of α-synuclein aggregation in human dopaminergic neurons in response to fibrils derived from individuals with Parkinson’s disease or multiple system atrophy.