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Synthetic microbe communities provide internal reference standards for metagenome sequencing and analysis

Authors :
Simon A. Hardwick
Wendy Y. Chen
Ted Wong
Bindu S. Kanakamedala
Ira W. Deveson
Sarah E. Ongley
Nadia S. Santini
Esteban Marcellin
Martin A. Smith
Lars K. Nielsen
Catherine E. Lovelock
Brett A. Neilan
Tim R. Mercer
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Complex microbial communities pose a challenge to metagenomic analysis. Here the authors develop ‘sequins’, internal DNA standards that represent a synthetic community of artificial genomes.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.b9f1c1f4bb54a1cb1792bb0e5f72ff5
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-05555-0