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Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments

Authors :
Jens Lipka
Manuela Semmler-Behnke
Alexander Wenk
Jana Burkhardt
Achim Aigner
Wolfgang Kreyling
Source :
Data in Brief, Vol 7, Iss , Pp 1175-1178 (2016)
Publication Year :
2016
Publisher :
Elsevier, 2016.

Abstract

Biokinetics data of lung-administered PEI F25-LMW/siRNA polyplexes within different lung compartments are presented. Thereby, at three different timepoints (1 h, 3 h, 8 h), the data was determined by calculations to the 32P-radioactivity in the whole mouse body. Additionally, data was optimized to the available PEI F25-LMW/siRNA polyplexes in the target organ and therefore normalized to the sum of all lung compartments. Methods, other biokinetics data and the discussion of the results are published in “Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice” (Lipka et al., 2016 [1]). Keywords: Biokinetic data, Lung, PEI

Details

Language :
English
ISSN :
23523409
Volume :
7
Issue :
1175-1178
Database :
Directory of Open Access Journals
Journal :
Data in Brief
Publication Type :
Academic Journal
Accession number :
edsdoj.b9eca9bf1ed344759ce3278a70432837
Document Type :
article
Full Text :
https://doi.org/10.1016/j.dib.2016.03.092