Back to Search
Start Over
MiR‐182‐5p enhances in vitro neutrophil infiltration in Kawasaki disease
- Source :
- Molecular Genetics & Genomic Medicine, Vol 7, Iss 12, Pp n/a-n/a (2019)
- Publication Year :
- 2019
- Publisher :
- Wiley, 2019.
-
Abstract
- Abstract Background Kawasaki disease (KD) patients could develop coronary artery lesion (CAL) which threatens children's life. A previous study identified KD biomarker miRNAs that could discriminate KD patients from febrile non‐KD patients. We wonder whether these KD prediction biomarkers could be further applied to predict CAL formation in KD patients. Methods To examine this hypothesis, we conducted a meta‐analysis, miRNA mimic transfection, in vitro cell model and microarray assays. Results We first showed that miR‐182‐5p and miR‐183‐5p kept higher levels in the KD patients with CAL than those without CAL (p
Details
- Language :
- English
- ISSN :
- 23249269
- Volume :
- 7
- Issue :
- 12
- Database :
- Directory of Open Access Journals
- Journal :
- Molecular Genetics & Genomic Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.b960e7d8067e43369a2bd025a9701583
- Document Type :
- article
- Full Text :
- https://doi.org/10.1002/mgg3.990