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Priming conditions shape breadth of neutralizing antibody responses to sarbecoviruses

Authors :
Janice Zhirong Jia
Chee Wah Tan
Samuel M. S. Cheng
Haogao Gu
Aileen Ying Yan Yeoh
Chris Ka Pun Mok
Yanqun Wang
Jincun Zhao
Nancy H. L. Leung
Benjamin J. Cowling
Leo L. M. Poon
David S. C. Hui
Linfa Wang
Malik Peiris
Sophie A. Valkenburg
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Vaccination and infection history determine the breadth of neutralizing antibody response to SARS-CoV-2 variants and other sarbecoviruses with breakthrough or natural infection combined with vaccination or booster vaccination with mRNA vaccine providing highest neutralization.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.b945fc7acc44408dababd01fdb84c979
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-34038-6