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Striatal D1 and D2 receptor availability are selectively associated with eye-blink rates after methylphenidate treatment

Authors :
Şükrü B. Demiral
Peter Manza
Erin Biesecker
Corinde Wiers
Ehsan Shokri-Kojori
Katherine McPherson
Evan Dennis
Allison Johnson
Dardo Tomasi
Gene-Jack Wang
Nora D. Volkow
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

PET imaging in human participants revealed that D1 and D2 dopamine receptor availability was associated with eye-blink rates following treatment with oral methylphenidate, but not a placebo.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.b8bf127aee141bca5ac632e6ce5563f
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-03979-5