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Impact of process stress on protein stability in highly-loaded solid protein/PEG formulations from small-scale melt extrusion
- Source :
- International Journal of Pharmaceutics: X, Vol 5, Iss , Pp 100154- (2023)
- Publication Year :
- 2023
- Publisher :
- Elsevier, 2023.
-
Abstract
- As protein-based therapeutics often exhibit a limited stability in liquid formulations, there is a growing interest in the development of solid protein formulations due to improved protein stability in the solid state. We used small-scale (
Details
- Language :
- English
- ISSN :
- 25901567
- Volume :
- 5
- Issue :
- 100154-
- Database :
- Directory of Open Access Journals
- Journal :
- International Journal of Pharmaceutics: X
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.b851d355ce5e4bad8679f702c11c2eb0
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.ijpx.2022.100154