Fluorescence molecular imaging probes for molecularclassification of breast cancer

At present, clinical diagnosis of breast cancer is based on the combination of pathological typesand molecular typing (immunohistochemistry). Yet, it is invasive and unable to show the relationship between keybiological molecules and clinical key information in situ and in real time. This paper introduces the latest researchprogress of molecular classification of breast cancer using molecular imaging technology. Fluorescence imaginghas high sensitivity and does not rely too much on image analysis. Thus, molecular classification information ofbreast cancer can be obtained in real time and multi-channel, quantitatively or semi quantitatively by using the cor‐responding fluorescent probes. Therefore, the development of safe and efficient near-infrared fluorescent molecu‐lar probes with strong tissue penetration is the focus of future fluorescence imaging technology and molecular clas‐sification of breast cancer