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Long non-coding RNA-dependent mechanism to regulate heme biosynthesis and erythrocyte development

Authors :
Jinhua Liu
Yapu Li
Jingyuan Tong
Jie Gao
Qing Guo
Lingling Zhang
Bingrui Wang
Hui Zhao
Hongtao Wang
Erlie Jiang
Ryo Kurita
Yukio Nakamura
Osamu Tanabe
James Douglas Engel
Emery H. Bresnick
Jiaxi Zhou
Lihong Shi
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

LncRNAs modulate diverse physiological cellular processes, however, their involvement in heme-dependent processes are not yet clear. Here the authors reveal the role of lncRNA UCA1 in erythroid cell development.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.b77cd360ed4e47e48a6cfe13667efaf8
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-06883-x