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SHAPE-guided RNA structure homology search and motif discovery

Authors :
Edoardo Morandi
Martijn J. van Hemert
Danny Incarnato
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-7 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

SHAPEwarp is a method that allows identifying structurally-similar RNAs by direct comparison of reactivity profiles derived from chemical probing experiments. Its application to viral genomes identified conserved RNA structure elements.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.b7606ea8e6514010bc06b4d57ae1ee13
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-29398-y