Research progress in applications used for guided tissue regeneration in endodontic surgery

Conventional root canal therapy can not completely treat all periradicular lesions, especially combined endodontic⁃periodontic diseases, large periapical lesions and bone defect lesions. Guided tissue regeneration greatly im⁃ proves the success rate of endodontic surgery in treating these lesions. This article focuses on the application of various grafting materials, guided bone regeneration membranes and regulatory factors in endodontic surgery.