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Noninvasive Method for Monitoring Pneumocystis carinii Pneumonia

Authors :
Michael J. Linke
Sandy Rebholz
Margaret Collins
Reiko Tanaka
Melanie T. Cushion
Source :
Emerging Infectious Diseases, Vol 9, Iss 12, Pp 1613-1616 (2003)
Publication Year :
2003
Publisher :
Centers for Disease Control and Prevention, 2003.

Abstract

The progression of Pneumocystis carinii pneumonia was temporally monitored and quantified by real-time polymerase chain reaction of P. carinii–specific DNA in oral swabs and lung homogenates from infected rats. DNA levels correlated with the number of P. carinii organisms in the rats’ lungs, as enumerated by microscopic methods. This report is the first of a noninvasive, antemortem method that can be used to monitor infection in a host over time.

Details

Language :
English
ISSN :
10806040 and 10806059
Volume :
9
Issue :
12
Database :
Directory of Open Access Journals
Journal :
Emerging Infectious Diseases
Publication Type :
Academic Journal
Accession number :
edsdoj.b74cec09424441b598af15ba66a038ee
Document Type :
article
Full Text :
https://doi.org/10.3201/eid0912.030270