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Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia

Authors :
Chun Chieh Fan
John J. McGrath
Vivek Appadurai
Alfonso Buil
Michael J. Gandal
Andrew J. Schork
Preben Bo Mortensen
Esben Agerbo
Sandy A. Geschwind
Daniel Geschwind
Thomas Werge
Wesley K. Thompson
Carsten Bøcker Pedersen
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Schizophrenia (SCZ) risk is influenced by genetic and environmental factors. Here, the authors develop a statistical method for analyzing gene-by-environment effects in SCZ risk across Denmark with fine spatial resolution.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.b7449a7728a54638a2286add760066c3
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-07708-7